Senior Laboratory Operations Technician

ANGLE is a world-leading liquid biopsy company commercialising a patent protected platform technology that can capture rare circulating tumour cells (CTCs) from blood, in a minimally invasive way, for downstream analysis.

ANGLE’s Parsortix® system is FDA cleared for its intended use in metastatic breast cancer and is currently the first and only FDA cleared medical device to harvest intact circulating cancer cells from blood. Parsortix technology comprises a microfluidic device that captures CTCs from blood based on their size and compressibility. CTCs are cancer cells that have detached from the primary tumour and entered the blood circulation, and they play a critical role in initiating metastasis. Once harvested, the CTCs can be comprehensively analysed to provide a wealth of information about the patient’s tumour, advancing cancer research and potentially personalized medicine. This technology has the potential to deliver profound improvements in clinical and health economic outcomes.

ANGLE has established a CTC harvest and analysis service from our UK-based Clinical Laboratory based in Guildford for customers worldwide. In alignment with company priorities, we plan to rapidly expand our services to include molecular profiling of CTCs and ctDNA using digital PCR and NGS to add to our image-based assays.

This is an exciting time at ANGLE and our team in Guildford are looking for a Senior Laboratory Operations Technician to contribute to the smooth running of the laboratory, providing operations support to the wider scientific team while working within the laboratory Management group.

At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading edge translational research into clinical diagnostics. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas.

We are always in search of potential employees who share our vision and want to make a difference today. In your submission, please describe your background and what you can bring to our team along with attaching your resume.

• Responsible for quality and regulatory compliance of work undertaken.
• Support in document writing; updating and reviewing current SOP’s and WI’s procedures.
• Assisting in laboratory document monitoring tasks including collection, organisation and revision of documents.
• Contribute to the smooth running of laboratory facility; cleaning laboratory/equipment as required.
• Complete stock checks, process orders and handle Internal laboratory goods to ensure all required stock is maintained at the correct levels.
• Formulate buffers and prepare various reagents for the laboratory in accordance with laboratory QMS.
• Handle hazardous materials, reagents, chemicals and compressed gases in a safe manner in accordance with laboratory policies and procedures.
• Ensure all consumables and reagents are labelled correctly in accordance with the laboratory Quality Management System (QMS).
• Arrange for equipment to be calibrated and/or serviced only when support is required within the team. Remaining a back-up for supporting the correct management of defective instruments, including carrying out instrument acceptance tests and maintaining associated records within the laboratory QMS. Ensure equipment is labelled correctly in accordance with laboratory QMS.
• Support in organising in house calibration or checks for laboratory equipment when required.
• Support all aspects of Laboratory Management in a variety of tasks both in and out of the laboratory as and when required by line manager; to include but not limited to laboratory administration and operations support.
• Assist in communication with suppliers and service providers.
• Contribute to weekly maintenance Parsortix instruments in accordance with laboratory SOPs.
• Work in accordance with laboratory Standard Operating Procedures (SOP’s), ensuring adherence to Health and Safety standards in the laboratory areas, as well as other laboratory standards.
• Supporting the Laboratory Supervisor in the training of other staff
• Undertake additional ad-hoc tasks as required.

• A Levels and proven, track-record of relevant laboratory experience or BSc in a relevant subject
• Experience of working to strict quality standards such as ISO9001 or preferably ISO13485 would be a significant advantage
• Organisational skills and the ability to follow agreed procedures are essential
• Demonstrated ability to manage teams and prioritize tasks in complex projects
• Manage and deliver production to agreed timetables and according to defined instructions
• Strong team player with excellent communication skills, work ethic and attention to detail
• Good report writing skills, with the ability to communicate results to technical and non-technical staff
• Strong verbal and written communication skills
• Ability to multitask and prioritise to meet deadlines
• Ability to work both independently with minimal supervision as well as in a team environment
• Continuous learner with a keen appetite for cross-disciplinary work
• Entrepreneurial thinking and work ethic
• An eye for detail and commitment to high-quality data
• A flexible, can-do approach to the requirements of the job

Due to the nature of the role, our requirement is for this position to be Guildford-based, office hours, five days per week.

As a member of our highly skilled team you will receive opportunities for training and development and a competitive benefits package.

​Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs.

Furthermore, please be advised that if you submit an application to us for this position, your application and personal details will be processed in accordance with our Data Privacy Notice for Job Candidates.