Product Development and Support Engineer

Guildford, UK

ANGLE is a world-leading liquid biopsy company with offices in Guildford (UK), Toronto (Canada) and Philadelphia (US).  ANGLE’s proven patent protected liquid biopsy platform products have the potential to be used in cancer diagnostics to enable early, accurate identification of an individual’s condition for the prevention, treatment, and monitoring of disease.

With 1 in 2 UK people being diagnosed with cancer in their lifetime*, ANGLE’s liquid biopsy technologies have the potential to help clinicians select the most appropriate drugs and therapies for an individual patient. As such, our technologies support the development of Precision Medicine.

In 2021 we opened GCLP compliant clinical laboratories in Guildford (UK) and Philadelphia (USA) to provide “pharma services” for cancer drug trials and, once the labs are accredited, laboratory developed tests (LDTs) for patient management. The pharma services business offers dynamic analysis of patient condition before, during and after the patient receives the drug, assessing both CTCs and CTC clusters recovered from a simple blood test. We are also pursuing an FDA product clearance for the Parsortix system and have submitted a full De Novo submission, which is currently in substantive review with FDA.

*Source: Cancer – NHS (

This is an exciting time at ANGLE and our research and development facilities in Guildford, UK are looking for a Product Development and Support Engineer specialising in development, design, inspection, analysis, improvement, and control of mechanical, fluidic, electrical, and electronic components of ANGLE’s products and in biotechnology process applications.

This important position, will undertake work that will help us to provide in-depth technical support to ANGLE customers and collaborators with research and development questions related to ANGLE technologies and adapting applications. You will be required to work on projects for the internal development (design, investigation, improvement, optimisation, and validation) of ANGLE’s products.

Principal Accountabilities:

  • Report to designated line manager but collaborate as instructed with specified project managers in activities that require product development or support.
  • Contribute to the development of existing diagnostic products, associated systems and test environments and the concept and design of new products.
  • Perform experimental design and undertake physical and fluid mechanical performance evaluation of the company’s circulating cell isolation products.
  • Build, test and evaluate prototype designs.
  • Develop and test approaches for the assessment of product functionality; specifically investigating factors that affect performance and reliability.
  • Provide technical support to internal and external customers and collaborators for diagnosing, rectifying, and preventing causes of instrument issues or failures.
  • Participate in product failure and root cause investigations, for example by utilising the company’s Customer Relationship Management (CRM) system to log and respond to technical support queries as well as for analysis such as FMEA.
  • Engineer and instrument devices with electronic and/or thermo-mechanical or acoustic sensors for the characterization of the company’s products.
  • Aid the optimisation of product engineering (e.g., sampling and collecting mechanisms, fluidic path components, sensors and actuators).
  • Develop, code and test operating protocols (using a proprietary scripting language) to support application and assay development.
  • Execute and manage product development activities in compliance with the Company’s NPD system.
  • Manage the development and delivery of sub-projects.

Qualifications, Experience, Knowledge and Attributes:

  • At a minimum first-degree level education in Biomedical, Chemical, Mechanical, Electrical, Electronics or another applicable engineering specialty is essential.
  • Minimum two years industrial, hands-on experience with mechanical, fluidic, pneumatic, electrical and electronic components, preferably in systems of lab bench or desk size.
  • Highly desirable experience in:
    – Biotechnology (Medical Devices, Life Sciences, Pharmaceutics) and training in laboratory environment.
    – Microelectromechanical and microfluidic systems.
    – In-vitro diagnostics systems and devices
  • Computer skills: Proficient with Microsoft Office Suite (Windows, Word, Excel, Outlook) and CAD software (SolidWorks preferred, capable of development of detailed CAD models and drawings), and conversant with CFD or FEA simulation tool (ANSYS preferred) and Project Management software, with the ability to learn new applications.
  • Data analysis capabilities are essential.
  • An eye for detail and commitment to high quality data.
  • Excellent organization skills, ensuring deadlines and expectations are meant, with the ability to manage own workload with minimal supervision whilst maintaining flexibility in job role.
  • Excellent written and verbal communication, interpersonal and coordination skills.
  • Keen to gain understanding of key project management concepts and apply them throughout the project lifecycle, under PMI-PMBOK, PRINCE2 or other structured methodologies.
  • Commitment and self-motivation to providing outstanding product development management. • Continuous learner with a keen appetite for cross-disciplinary work.
  • Strong team player with excellent communication skills.
  • Commercially astute and dynamic strategic thinker with significant leadership potential. • Entrepreneurial thinking and work ethic.
  • Possess a flexible, can-do approach to the requirements of the job including additional ad-hoc tasks. • Be keen to develop with a company long term.

Due to the nature of the role, our requirement is for this position to be Guildford based, office hours, five days per week.

Join our Team

At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading edge translational research into clinical diagnostics. We offer the potential for significant corporate growth and career development. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas.

We are always in search of potential employees who share our vision and want to make a difference today. In your submission, please note the position you are interested in, describe your background and what you can bring to our team along with attaching your resume.

As a member of our excellent and fast-growing team you will receive opportunities for development and a competitive benefits package.

Salary estimate – £32000

Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs.

If you submit an application to us, your application and personal details will be processed in accordance with our Data Privacy Notice for Job Candidates.

Important notice to Employment Businesses/ Agencies
ANGLE does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact our ANGLE recruitment team to obtain prior written authorisation before referring any candidates. In the absence of such written authorisation being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of ANGLE. ANGLE shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.



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