Scientist I (Cell Biology & Imaging)

Guildford, UK

ANGLE is a world-leading liquid biopsy company with offices in Guildford (UK), Toronto (Canada) and the Greater Philadelphia area (USA). ANGLE’s patented liquid biopsy platform and associated assays have the potential to be used throughout the cancer care pathway to provide clinicians with individualised, up-to-date, and clinically actionable insight into every patient’s cancer. This could enable patients to receive timely, personalised treatment and improve clinical outcomes.

Liquid biopsies involve sampling and analysis of peripheral blood to identify signs of cancer. Liquid biopsy is minimally invasive and can be undertaken safely in community clinics to provide patients with a rapid diagnosis and timely treatment with targeted therapies. Liquid biopsy may also help to safely monitor cancer patients in remission to provide early warning of recurrence.

In 2021 ANGLE opened GCLP compliant clinical laboratories in Guildford (UK) and Philadelphia (USA) to provide “pharma services” for cancer drug trials and, once the labs are accredited, laboratory developed tests (LDTs) for patient management.

In May 2022, ANGLE achieved FDA clearance for a novel medical device for the capture and harvest of circulating tumour cells (CTCs) from metastatic breast cancer patient blood for subsequent analysis

Join our Team:

This is an exciting time at ANGLE, and our research and development facilities in Guildford are looking for a Scientist I to join the Cell Biology and Imaging Team.

The successful candidate will work as part of a multi-disciplinary team to contribute to the development of clinical diagnostic assays and products. While the role is mainly laboratory-based, a substantial amount of time will be spent performing analysis of the data acquired in the laboratory and writing experimental specifications and reports.

The candidate will receive extensive training in the techniques most commonly used in the laboratory, as well as in data gathering, data analysis and document writing. Performance will be checked in regular meetings with the line manager, giving the job holder the opportunity to assess their contribution to the projects and the team, and to grow professionally and personally in the work setting.

Whilst experimental goals are agreed on a weekly basis by the line managers and daily support is offered, an ability to work independently is expected.

At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading edge translational research into clinical diagnostics. We offer the potential for significant corporate growth and career development. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas.

We are always in search of potential employees who share our vision and want to make a difference today. In your submission, please describe your background and what you can bring to our team along with attaching your resume.

Principal Accountabilities:

  • Hands-on laboratory work, primarily in the area of Cell Biology and Imaging.
  • Provide scientific and technical support to projects.
  • Responsible for on-time delivery of project goals, including timely reporting of progress to ensure project deadlines are met.
  • Responsible for quality and regulatory compliance of the work undertaken.
  • Independently keep a current base knowledge in relevant areas of scientific and technical research.
  • Manage the day to day running of assigned projects within the Quality Management System (ISO13485) and working to the New Product Development (NPD) operating procedure.
  • Undertake additional adhoc / project work as required.

Qualifications, Experience, Knowledge and Attributes:

  • Bachelor in Life Sciences with relevant laboratory experience or Masters in Life Sciences, with at least 1 year’s laboratory experience in Oncology, Cell Biology or Imaging (preferably gained in the in vitro diagnostics assay development/validation industry). Or, an equivalent combination of professional/relevant experience and formal education.
  • Demonstrable competency in Cell Biology and Imaging methods.
  • Immunofluorescence staining methods.
  • Experience working to strict quality standards such as Medical Device Regulations including, but not limited to, 21 CFR 820, ISO 13485, 93/42/EEC, IVD 98/79 EC, ISO14971, GMP, GLP, QSR. A strong understanding of the importance of accurate record keeping within a strictly controlled quality system is essential.
  • Deliver experiments on time to agreed performance specifications.
  • Organisational skills and the ability to rapidly prioritise tasks in response to unexpected changes.
  • Ability to multitask and prioritise to meet deadlines.
  • Strong team player with excellent communication skills, work ethic and attention to detail.
  • Strong verbal and written communication skills.
  • Ability to work both independently as well as in a team environment.
  • Continuous learner with a keen appetite for cross-disciplinary work.
  • A flexible, can-do approach to the requirements of the job.
  • Product development thinking and an excellent work ethic.

Due to the nature of the role, our requirement is for this position to be Guildford based, office hours, five days per week.

As a member of our highly skilled and fast-growing team you will receive opportunities for development and a competitive benefits package.

Salary estimate – £28,400 per annum

Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs.

Furthermore, please be advised that if you submit an application to us for this position, your application and personal details will be processed in accordance with our Data Privacy Notice for Job Candidates.

Important notice to Employment Businesses/ Agencies

ANGLE does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact our ANGLE recruitment team to obtain prior written authorisation before referring any candidates. In the absence of such written authorisation being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of ANGLE. ANGLE shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.


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