Scientist I (Cell Biology & Imaging)

Guildford, UK

ANGLE is a world-leading liquid biopsy company with offices in Guildford (UK), Toronto (Canada) and Philadelphia (US). ANGLE’s proven patent protected liquid biopsy platform products have the potential to be used in cancer diagnostics to enable early, accurate identification of an individual’s condition for the prevention, treatment, and monitoring of disease.

Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020*. ANGLE’s liquid biopsy technologies have the potential to help clinicians select the most appropriate drugs and therapies for an individual patient. As such, our technologies support the development of Precision Medicine.

In 2021 we opened GCLP compliant clinical laboratories in Guildford (UK) and Philadelphia (USA) to provide “pharma services” for cancer drug trials and, once the labs are accredited, laboratory developed tests (LDTs) for patient management. The pharma services business offers dynamic analysis of patient condition before, during and after the patient receives the drug, assessing both CTCs and CTC clusters recovered from a simple blood test. We are also pursuing an FDA product clearance for the Parsortix system and have submitted a full De Novo submission, which is currently in substantive review with FDA.

*IARC, WHO Cancer (who.int)

This is an exciting time at ANGLE and our research and development facilities in Guildford, UK are
looking for a Scientist 1 specialising in Cell Biology & Imaging.

This important position contributes to the management of the laboratory and the development of imaging and cell biology assays and provides technical and scientific support to the R&D team. The job is laboratory-based working in a multi-disciplinary team. Goals and routes are agreed weekly with supervisor, but an ability to work independently is expected.

The job holder will learn to follow standard operating procedures and handling instruments and reagents commonly used in biological labs. Moreover, the job holder will be able to present their progress in weekly group updates and understand the effects of their technical work supporting the team.

This position provides invaluable lab experience and teamwork skills, and the opportunity to actively contribute to product development in an industry environment.

Principal Accountabilities:

  • Hands-on laboratory work preliminary in the area of Cell Biology and Imaging, performing regular lab techniques: preparing and processing blood samples using the Parsortix instrument, processing samples on slides, IF staining and imaging samples using microscopes.
  • Responsible of data collection and recording according to ANGLE quality regulations
  • Involved in data processing, analysis and reporting (with support when and if needed)
  • Provide scientific and technical support to other members of the team in various programs and projects in the area of Cell Biology and Imaging
  • Responsible for quality and regulatory compliance of work undertaken
  • Independently keep a current knowledge base in relevant areas of scientific and technical research;
  • Support all aspects of Laboratory Management in a variety of tasks both in and out of the lab as and when required by line manager
  • Undertake additional ad-hoc tasks as required.

Qualifications, Experience, Knowledge and Attributes:

  • B.Sc. or equivalent in Life Sciences gained on a course that includes practical laboratory work with at least 5 years of relevant laboratory experience or equivalent in oncology and cell biology or imaging, or Masters in Life Sciences, with at least 2 years of relevant laboratory experience in oncology and cell biology or imaging, preferably gained in the in vitro diagnostics industry in diagnostic assay development/validation
  • Demonstrated expertise and hand-on competency in cell biology and imaging technologies
  • Immunofluorescence assay development is essential
  • Experience of working to strict quality standards such as ISO9001 or preferably ISO3485 would be an advantage
  • Organisational skills and the ability to rapidly prioritise tasks in response to unexpected opportunities or risks
  • Strong team player
  • Strong verbal and written communication skills
  • Ability to multitask and prioritise to meet deadlines
  • Ability to work both independently with minimal supervision as well as in a team environment
  • An eye for detail and commitment to high quality data
  • Continuous learner with a keen appetite for cross-disciplinary work
  • A flexible, can-do approach to the requirements of the job
  • Entrepreneurial thinking and work ethic
  • Due to the nature of the role, our requirement is for this position to be Guildford based, office hours, five days per week.

Join our Team

At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading edge translational research into clinical diagnostics. We offer the potential for significant corporate growth and career development. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas.

We are always in search of potential employees who share our vision and want to make a difference today. In your submission, please note the position you are interested in, describe your background and what you can bring to our team along with attaching your resume.

As a member of our excellent and fast-growing team you will receive opportunities for development and a competitive benefits package.

Salary estimate – £27000

Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs.

Important notice to Employment Businesses/ Agencies
ANGLE does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact our ANGLE recruitment team to obtain prior written authorisation before referring any candidates. In the absence of such written authorisation being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of ANGLE. ANGLE shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

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