Scientist I (Engineering)

Guildford, UK

ANGLE is a world-leading liquid biopsy company with offices in Guildford (UK), Toronto (Canada) and Greater Philadelphia area (USA). ANGLE’s patented liquid biopsy platform and associated assays have the potential to be used throughout the cancer care pathway to provide clinicians with individualised, up-to-date, and clinically actionable insight into every patient’s cancer. This could enable patients to receive timely, personalised treatment and improve clinical outcomes.

Liquid biopsies involve sampling and analysis of peripheral blood to identify signs of cancer. Liquid biopsy is minimally invasive and can be undertaken safely in community clinics to provide patients with a rapid diagnosis and timely treatment with targeted therapies. Liquid biopsy may also help to safely monitor cancer patients in remission to provide early warning of recurrence.

In 2021 ANGLE opened GCLP compliant clinical laboratories in Guildford (UK) and in the Greater Philadelphia area (USA) to provide “pharma services” for cancer drug trials and, once the labs are accredited, laboratory developed tests (LDTs) for patient management.

In May 2022, ANGLE achieved FDA clearance for a novel medical device for the capture and harvest of circulating tumour cells (CTCs) from metastatic breast cancer patient blood for subsequent analysis.

Join our Team:

This is an exciting time at ANGLE and our research and development facilities in Guildford, UK are looking for a Scientist I specialising in Biological Engineering.

This important position, will join ANGLE’s Product and Technology Development (PTD) team to primarily support the development of the Parsortix® Technology. In brief, we are looking for a candidate who is keen to work in a skilled interdisciplinary team at the interface of Biology and Engineering. The candidate will be a pro-active team player contributing to the smooth running of our laboratory by providing technical support to the scientific and engineering team, developing clinical diagnostic products. Due to the inherent nature of product development work, it is expected that the candidate is comfortable with repetitious work and that they can demonstrate a good eye for detail through constant observation. Goals and routes are agreed weekly with the supervisor, but an ability to work independently is expected.

At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading edge translational research into clinical diagnostics. We offer the potential for significant corporate growth and career development. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas.

We are always in search of potential employees who share our vision and want to make a difference today. In your submission, please describe your background and what you can bring to our team along with attaching your resume.

Principal Accountabilities:

  • Hands-on laboratory bench work, primarily in the area of medical device development.
  • Provide scientific and technical support to programmes and projects.
  • Responsible for on-time and on-budget delivery of work packages within a project, including timely reporting of progress on projects and on metrics to monitor and mitigate risk and to ensure product deadlines are met.
  • Responsible for quality and regulatory compliance of work undertaken.
  • Independently keep a current knowledge base in relevant areas of scientific and technical research.
  • Manage the day to day running of assigned development projects within the Quality Management System (ISO13485:2016) and working to the New Product Development (NPD) operating procedure.
  • Undertake additional adhoc / project work as required.

Qualifications, Experience, Knowledge and Attributes:

  • Sc. in either Life Sciences or Engineering.
  • Basic laboratory skills including but not limited to, pipetting and reagent preparation.
  • Experience working to strict quality standards such as Medical Device regulations and standards including, but not limited to, 21 CFR 820, ISO 13485, 93/42/EEC, IVD 98/79 EC, ISO14971, GMP, GLP, QSR.
  • A strong understanding of the importance of accurate record keeping within a strictly controlled quality system is essential.
  • Manage and deliver product development projects to agreed performance specifications, on time and within budget.
  • Organisational skills and the ability to rapidly prioritise tasks in response to unexpected opportunities or risks.
  • Excellent accuracy and attention to detail in practical and written work.
  • Strong team player with excellent analytical and interpersonal skills.
  • Good report writing skills, with the ability to communicate results to technical and non-technical staff.
  • Ability to work independently with minimal supervision.
  • Continuous learner with a keen appetite for cross-disciplinary work.
  • A flexible, can-do approach to the requirements of the job.
  • Entrepreneurial thinking and work ethic.

Due to nature of role, the requirement is for Guildford based, office hours and 5 days per week, with flexibility to work shift patterns if required.

As a member of our highly skilled and fast-growing team you will receive opportunities for development and a competitive benefits package.

Salary estimate – £28,400 per annum

Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs.

Furthermore, please be advised that if you submit an application to us for this position, your application and personal details will be processed in accordance with our Data Privacy Notice for Job Candidates.

Important notice to Employment Businesses/ Agencies

ANGLE does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact our ANGLE recruitment team to obtain prior written authorisation before referring any candidates. In the absence of such written authorisation being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of ANGLE. ANGLE shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.


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