Scientist II

Guildford, UK

ANGLE is a world-leading liquid biopsy company with offices in Guildford (UK), Toronto (Canada) and Philadelphia (US). ANGLE’s proven patent protected liquid biopsy platform products have the potential to be used in cancer diagnostics to enable early, accurate identification of an individual’s condition for the prevention, treatment, and monitoring of disease.

Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020*. ANGLE’s liquid biopsy technologies have the potential to help clinicians select the most appropriate drugs and therapies for an individual patient. As such, our technologies support the development of Precision Medicine.

In 2021 we opened GCLP compliant clinical laboratories in Guildford (UK) and Philadelphia (USA) to provide “pharma services” for cancer drug trials and, once the labs are accredited, laboratory developed tests (LDTs) for patient management. The pharma services business offers dynamic analysis of patient condition before, during and after the patient receives the drug, assessing both CTCs and CTC clusters recovered from a simple blood test. We are also pursuing an FDA product clearance for the Parsortix system and have submitted a full De Novo submission, which is currently in substantive review with FDA.

*IARC, WHO Cancer (

This is an exciting time at ANGLE and our research and development facilities in Guildford, UK are looking for a Scientist II specialising in Molecular Biology

You will be a Scientist II who can apply considerable innovation resulting in a major impact on company performance.

This important position, is primarily responsible for methods development and validation in support of clinical diagnostic products. An important aspect of this position is support of other projects/programs within the Company and the establishment of company-wide methods and SOP’s relative to Molecular Biology (in particular PCR).

The job is laboratory-based and office-based, working in a multi-disciplinary team responsible for aspects of the development and validation of ANGLE’s clinical diagnostic products.

The ability to think ahead in a complex environment to solve problems and make recommendations to the Group Leader on proposed routes is expected.

Principal Accountabilities:

  • Hands-on laboratory work, primarily in the area of Molecular Biology (in particular PCR)
  • Responsible for on-time and on-budget delivery of work packages within a project
  • Act as Project leader on one project as required
  • Responsible to ensuring quality and regulatory compliance of projects;
  • Timely reporting of progress on projects and on metrics to monitor and mitigate risk and to ensure product deadlines are met
  • Manage the day to day running of assigned development projects within the Quality Management System (ISO13485) and working to the New Product Development (NPD) operating procedure
  • Provide scientific and technical support to programmes and projects
  • Provide scientific expertise, advice and practical support to senior management in all technical areas of the company
  • Independently keep a current knowledge base in areas of scientific and technical research, making recommendations on new processes, technologies and product opportunities
  • Undertake additional adhoc / project work as required

Qualifications, Experience, Knowledge and Attributes:

  • PhD in Life Sciences, or MSc with at least 3 years experience or equivalent in oncology, molecular biology, preferably gained in the in vitro diagnostics industry in diagnostic assay development/validation;
  • Demonstrated expertise and hand-on competency in molecular technologies and in particular in PCR;
  • Experience in digital droplet PCR is an advantage;
  • Experience working to strict quality standards such as Medical Device regulations and standards including, but not limited to, 21 CFR 820, ISO 13485, 93/42/EEC, IVD 98/79 EC, ISO14971, GMP, GLP, QSR;
  • Excellent oral and written communication skills
  • Organisational skills and the ability to rapidly prioritise tasks in response to unexpected opportunities or risks
  • Effective time management and an ability to delegate work to team members and manage delivery
  • Experimental design and project/resource planning skills
  • Ability to manage and coordinate the timely creation and delivery of project reports
  • Manage and deliver product development projects to agreed performance specifications, on time and within budget
  • Strong team player with excellent communication skills
  • Commercially astute and a dynamic, strategic thinker
  • Possess a flexible, can-do approach to the requirements of the job
  • Strong verbal and written communication skills
  • Ability to multitask and prioritise to meet deadlines
  • Ability to work both independently with minimal supervision as well as in a team environment
  • An eye for detail and commitment to high quality data
  • Continuous learner with a keen appetite for cross-disciplinary work
  • Entrepreneurial thinking and work ethic

Join our Team

At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading edge translational research into clinical diagnostics. We offer the potential for significant corporate growth and career development. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas.

We are always in search of potential employees who share our vision and want to make a difference today. In your submission, please note the position you are interested in, describe your background and what you can bring to our team along with attaching your resume.

As a member of our excellent and fast-growing team you will receive opportunities for development and a competitive benefits package.

Salary estimate – £32000

Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs.

Important notice to Employment Businesses/ Agencies
ANGLE does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact our ANGLE recruitment team to obtain prior written authorisation before referring any candidates. In the absence of such written authorisation being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of ANGLE. ANGLE shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.



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