Technology Solutions Research Associate – ANGLE Biosciences Inc., Toronto 

Toronto, Canada

ANGLE is a world-leading liquid biopsy company with offices in Guildford (UK), Toronto (Canada) and the  Greater Philadelphia area (US). ANGLE’s proven patent protected liquid biopsy platform products have the  potential to be used in cancer diagnostics to enable early, accurate identification of an individual’s condition for  the prevention, treatment, and monitoring of disease.

With 1 in 2 UK people being diagnosed with cancer in their lifetime*, ANGLE’s liquid biopsy technologies have  the potential to help clinicians select the most appropriate drugs and therapies for an individual patient. As such,  our technologies support the development of Precision Medicine.

In 2021 we opened GCLP compliant clinical laboratories in Guildford (UK) and the Greater Philadelphia area (US)  to provide “pharma services” for cancer drug trials and, once the labs are accredited, laboratory developed tests  (LDTs) for patient management. The pharma services business offers dynamic analysis of patient condition before,  during and after the patient receives the drug, assessing both CTCs and CTC clusters recovered from a simple  blood test.

We are also pursuing an FDA product clearance for the Parsortix system and have submitted a full De Novo  submission, which is currently in substantive review with FDA.

*Source: Cancer – NHS (www.nhs.uk) 

This is an exciting time at ANGLE and our Research and Development facilities in Toronto, we are looking for a Technology Solutions Research Associate. The role of the Research Associate is to execute laboratory tasks and  conduct scientific studies to advance platform and clinical assay development, verification and validation. Their  primary responsibility is to provide laboratory services in cell and molecular biology utilizing the company’s core  technologies.

They are also responsible for planning/conducting experiments, data analysis and writing scientific reports to  support product development and to innovate improvements to existing products and procedures. The Research Associate works in a regulated and multi-disciplinary environment requiring extensive inter departmental liaison and coordination.

The Research Associate works on projects that may require considerable innovation resulting in a major impact  on company performance, following set goals and determined route(s) to delivery. The incumbent works to  ensure success of projects, company goals and milestone delivery.

Essential Duties and Responsibilities:

  • Provide laboratory services in cell culture, blood processing (Parsortix), cell staining, immunoassay and gene  expression analysis for clinical assay and platform development activities
  • Participate in the development, optimization, verification, and validation of assays under design control in  support of corporate research and product development programs
  • Prepare experimental specification and report documents as assigned
  • Perform and accurately and formally document results from experimentation, device and assay designs and  verification tests in a timely manner
  • Implement design controls, verification, and validation strategies in compliance with relevant regulatory  guidelines and with minimal supervision
  • Collect, analyze, prepare, and present summaries of data
  • Develop and maintain laboratory procedures and equipment consistent with QSRs
  • Contribute to the development of new products and ideas through scientific studies, literature reviews and  observation
  • Represent the company externally as required through participation in partner projects and customer technical  support
  • Provide training to other staff members when assigned
  • Perform such other duties and responsibilities that are consistent with the role of a Research Associate or as  may be assigned from time to time

Required Experience, Education and Knowledge:

  • BSc in life sciences, preferably in the field of oncology, molecular biology, or cell biology OR an equivalent combination of commercial experience and formal education
  • 1-3 years research lab experience, preferably in an industrial biotechnology or diagnostic company operating in a regulated manufacturing or product development environment
  • 1-2 years of laboratory experience in at least one of the following: mammalian cell culture; cell staining; immunoassays; molecular biology; working with human blood
  • Proficient in routine laboratory skills (e.g. pipetting, operation of laboratory equipment)
  • Working knowledge of appropriate regulatory requirements (e.g. cGMP, ISO, WHMIS, Occupational Safety)
  • Proficiency in Microsoft Office (Excel, Word, PowerPoint)

Key Attributes:

  • Strong scientific/technical aptitude
  • Willingness and flexibility in undertaking new tasks
  • Strong team player with excellent interpersonal skills
  • Exceptional organizational and time management skills
  • Strong commitment to producing high quality results in support of project goals
  • Strong verbal and written communication skills
  • Ability to multitask and prioritize to meet deadlines
  • Ability to work both independently with minimal supervision as well as in a team environment
  • An eye for detail and commitment to high quality data
  • Continuous learner with a keen appetite for cross-disciplinary work
  • A flexible, can-do approach to the requirements of the job
  • Entrepreneurial thinking and work ethic

How to Apply

Please submit your resume, along with a cover letter to jobsABI@angleplc.com or apply directly to our website  at https://angleplc.com/careers/ 

Please reference the position: “Technology Solutions Research Associate”.

All applications will be kept confidential. We thank all candidates for their interest, but only candidates selected  for an interview will be contacted.

Please no recruiters.

At ANGLE Biosciences Inc. we are committed to maintaining and developing a qualified workforce that reflects  the diverse population it serves, and we welcome applications from all qualified individuals. We value diversity and  we do not discriminate on the basis of race, religion, color, sex, age, non-disqualifying physical or mental disability,  national origin, sexual orientation, gender identity or expression, or any other basis covered by local law. We are also committed to preventing and removing barriers to employment for people with disabilities, and we invite you  to inform us should you have any accessibility or accommodation needs.

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