ANGLE has a standardised and fully integrated workflow for the enumeration and evaluation of epithelial and mesenchymal CTCs and CTC clusters. The workflow integrates:
- ANGLE’s Parsortix system for CTC capture (capturing both epithelial and mesenchymal phenotypes), together with;
- an optimised and customisable panel of antibodies for identification of the full range of CTCs (and exclusion of WBC), and;
- Bioview imaging solutions for the evaluation and enumeration of CTCs
How the service works
1
10ml whole blood sample
Send your patient blood samples to our laboratory.
2
Sample processing
Samples will be processed by ANGLE within 24 hours.
3
Image capture
Images of captured and characterised CTCs shared via secure cloud.
4
Data report
Report for each sample processed is shared back with you.
ANGLE is able to include specific protein markers according to your needs.
The performance of Parsortix technology has been demonstrated in multiple third party and peer reviewed publications. We would be pleased to share exemplary data obtained from our integrated enumeration workflow.
Example images from patient blood samples
Cluster of CK + CTCs (green) from breast cancer patient (20x)
Cluster of CK+ (green) and mesenchymal (red) CTCs from breast cancer patient (20x)
CK + CTC from breast cancer patient (40x)
Cluster of mesenchymal CTCs (red) from breast cancer patient (20x)
Research Use Only. Not for use in Diagnostic Procedures