Parsortix® Library
Publications: 70 peer-reviewed publications
For Research Use Only. Not for use in diagnostic procedures.
Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria, published by Breast Cancer Research and Treatment, September 2022
Institute of Head and Neck Studies and Education, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom, published by Head and Neck, July 2022
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Wilmot Cancer Institute, University of Rochester, Rochester, New York and ANGLE Europe Limited, Surrey Research Park, Guildford, Surrey, United Kingdom, published by Obstetrics & Gynecology, September 2022
Edith Cowan University, Perth, Australia, published by Journal of Cancer Research and Clinical Oncology, July 2022
University Hospital and Medical Faculty, Heinrich-Heine University Dusseldorf, Dusseldorf, Germany, published by Cytometry, June 2022
National and Kapodistrian University of Athens, Greece, published by Cancers, June 2022
National and Kapodistrian University of Athens, Greece, published by Clinical Epigenetics, May 2022
The metastatic spread of breast cancer accelerates during sleep
Molecular Oncology Laboratory at the Swiss Federal Institute of Technology (ETH) Zurich, Switzerland, published by Nature, June 2022
Evaluation of PD-L1 expression on circulating tumour cells in small-cell lung cancer
School of Medical and Health Sciences, Edith Cowan University, Perth, Australia, published by Translational Lung Cancer Research, May 2022
Invadopodia play a role in prostate cancer progression
School of Cancer and Pharmaceutical Sciences, King’s College London, London, UK, published by BMC Cancer, April 2022
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy, published by Clinical Chemistry, March 2022
An in vivo CRISPR screen identifies stepwise genetic dependencies of metastatic progression
Molecular Oncology Laboratory, Swiss Federal Institute of Technology (ETH) Zurich, Switzerland, published by Cancer Research, February 2022
Microtubule disruption reduces metastasis more effectively than primary tumor growth
University of Maryland Marlene and Stewart Greenebaum NCI Comprehensive Cancer Institute, Baltimore, Maryland, USA, published by Breast Cancer Research, February 2022
Universidad Autonoma de Madrid, Madrid, Spain, published by Frontiers in Pharmacology, January 2022
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy, published by Scientific Reports, January 2022
Edith Cowan University, Perth, Australia, published by Cancers, December 2021
Circulating Tumor Cell Transcriptomics as Biopsy Surrogates in Metastatic Breast Cancer
University of Southern California Norris Cancer Center, Los Angeles, United States, published by Annals of Surgical Oncology, January 2022
National and Kapodistrian University of Athens, Greece, published by Cancers, November 2021
Cancer Stem Cell-like Circulating Tumor Cells Are Prognostic in Non-Small Cell Lung Cancer
Molecular Oncology Group, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Austria, published by Journal of Personalized Medicine, November 2021
Institute of Head and Neck Studies and Education, Institute of Cancer and Genomic Sciences, University of Birmingham, UK, published by Cancers, November 2021
Liquid Biopsy Analysis Unit, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago (IDIS), Santiago de Compostela, Spain published by Molecular Oncology, August 2021
Department of Urology, Medical University Innsbruck, Innsbruck, Austria published by Biomedicines, August 2021
Whole-genome sequencing of single circulating tumor cells from neuroendocrine neoplasms
UCL Cancer Institute, University College London, London, UK, published by Endocrine-Related Cancer, July 2021
Department of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia published by Radiology and Oncology, July 2021
CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis
University Medical Center Hamburg-Eppendorf, Hamburg, Germany published by International Journal of Molecular Sciences, June 2021
National and Kapodistrian University of Athens, Greece published by Cancers, May 2021
Washington University School of Medicine, St. Louis, Missouri, United States published by PLoS ONE, May 2021
Department of Gastro-Intestinal Surgery, University Hospital Ghent, Belgium published by PLoS ONE, May 2021
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy published by ESMO Open / Cancer Horizons, March 2021
University Medical Centre Hamburg-Eppendorf, Hamburg, Germany published by Cancers, February 2021
National and Kapodistrian University of Athens, Greece published by Nature Scientific Reports, January 2021
The CANCER-ID Consortium published by Clinical Chemistry, January 2021
London Regional Cancer Program and Flow Cytometry, London Health Sciences Centre; Departments of Anatomy & Cell Biology and Oncology, Western University; and Lawson Health Research Institute, London, Ontario, Canada published by Clinical & Experimental Metastasis, January 2021
Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, United States published by PLOS ONE, October 2020
Hypoxia Triggers the Intravasation of Clustered Circulating Tumor Cells
Department of Bioscience, Cancer Metastasis Laboratory, University of Basel and University Hospital Basel, Switzerland published by Cell Reports, September 2020
Laboratory of Translational Oncology, School of Medicine, University of Crete, Greece published by Cancers, June 2020
University of Southern California Norris Comprehensive Cancer Center, Los Angeles, United States published by International Journal of Molecular Sciences, July 2020
Detection of MET Alterations Using Cell Free DNA and Circulating Tumor Cells from Cancer Patients
Liquid Biopsy Analysis Unit, Health Research Institute of Santiago, Spain published by Cells, February 2020
Cancer transcriptomic profiling from rapidly enriched circulating tumor cells
Keck School of Medicine, University of Southern California, United States published by International Journal of Cancer, February 2020
University of Athens, Greece published by Nature Scientific Reports, April 2020
University Medical Center Hamburg-Eppendorf, Hamburg, Germany published by Journal of Neuro-Oncology, February 2020
Fondazione IRCCS Istituto Nazionale Tumori, Milano, Italy published by International Journal of Molecular Sciences, February 2020
University Medical Center Hamburg-Eppendorf, Hamburg, Germany published by Cancers, February 2020
Detection and prognostic role of heterogeneous populations of melanoma circulating tumour cells
Edith Cowan University, Perth, Australia published by British Journal of Cancer, February 2020
University Medical Center Hamburg-Eppendorf, Hamburg, Germany published by Cancers, October 2019
Circulating Tumour Cell Biomarkers in Head and Neck Cancer: Current Progress and Future Prospects
Institute of Head and Neck Studies and Institute of Immunology and Immunotherapy, University of Birmingham, UK published by Cancers, August 2019
Non-invasive detection of clinically significant prostate cancer using circulating tumor cells
Barts Cancer Institute, Queen Mary University of London, UK published by Journal of Urology, September 2019
Medical University of Vienna, Austria published by Cells, August 2019
University Hospital and Medical Faculty of the Heinrich-Heine University Duesseldorf, Germany published by Cancers, June 2019
Department of Oncology, Hematology and Bone Marrow Transplantation with section Pneumology, Hubertus Wald University Comprehensive Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany published by Cancers, June 2019
Biomarker Research Program, Houston Methodist Research Institute in conjunction with the Center for Precision Health, University of Texas and MD Anderson Cancer Center, Houston, United States published by International Journal of Molecular Sciences, April 2019
Assessing metastatic potential of breast cancer cells based on EGFR dynamics
The University of Texas MD Anderson Cancer Center, Houston, United States published by Nature, March 2019
Disseminated Cancer Cell Network (DCCNet) at the University Hospital and Medical Faculty of the Heinrich-Heine University of Duesseldorf, Duesseldorf, Germany published by Clinical Chemistry, February 2019
Neutrophils escort circulating tumour cells to enable cell cycle progression
Cancer Metastasis Laboratory, University of Basel and collaborators published by Nature, February 2019
Fraunhofer Institute for Toxicology and Experimental Medicine, Regensburg, Germany published by International Journal of Cancer, January 2019
Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding
Cancer Metastasis Laboratory, University of Basel and collaborators published by Cell, January 2019
Cancer Metastasis Laboratory, University of Basel, Switzerland published by Breast Cancer Research, November 2018
Detection of circulating tumour cell clusters in human glioblastoma
Cancer Metastasis Laboratory, University of Basel and collaborators published by British Journal of Cancer, August 2018
The Parsortix® Cell Separation System – A Versatile Liquid Biopsy Platform
ANGLE plc published by Cytometry Part A, Journal of Quantitative Cell Science, July 2018
Department of Cellular Pathology, Musgrove Park Hospital, Taunton UK published by the Journal of Clinical Pathology, March 2018
Challenges in using liquid biopsies for gene expression profiling
University of Southern California Norris Comprehensive Cancer Center published by Oncotarget, January 2018
University Medical Centre Hamburg-Eppendorf, Medical University of Graz and Stockholm University published by Clinical Chemistry, January 2018
Medical University of Vienna published by Oncotarget, November 2017
Comparison of isolation platforms for detection of circulating renal cell carcinoma cells
Clinic for Urology, University Hospital Muenster, Muenster, Germany published by Oncotarget, September 2017
Heinrich Heine University of Dusseldorf published by International Journal of Molecular Sciences, August 2017
Barts Cancer Institute published by Clinical Cancer Research, June 2017
University Medical Centre Hamburg-Eppendorf (UKE) published by Clinical Chemistry, September 2016
University Medical Centre Hamburg-Eppendorf (UKE) published by International Journal of Cancer, January 2016
Cancer Research UK Manchester Institute and Christie NHS Foundation Trust, Manchester UK published by Royal Society of Chemistry Analyst publication, November 2015
Optimization and Evaluation of a Novel Size Based Circulating Tumor Cell Isolation System
Barts Cancer Institute, published by PLOS ONE on 23 September 2015
Posters: 39 publicly available posters
For Research Use Only. Not for use in diagnostic procedures.
Morphological Characteristics of Malignancy in Circulating Tumor Cells
ANGLE Onc-ADaPT Labs as presented at the 100th American Society of Clinical Pathology (ASCP) Meeting in Chicago, Illinois, USA September 2022
Antigen-independent enrichment of circulating tumour cells in metastatic breast and ovarian cancer
Trinity College Dublin as presented at EACR Liquid Biopsies Conference, May 2022
ANGLE plc and University of Rochester Medical Center, Wilmot Cancer Institute as presented at SGO, March 2020
ANGLE plc and University of Rochester Medical Center, Wilmot Cancer Institute as presented at SGO, March 2018
Barts Cancer Institute, Queen Mary University of London, UK as presented at NCRI Festival 8-12 November 2021
Medical University of Vienna, Austria as presented at the Fifth Advances in Circulating Tumour Cells (ACTC) Meeting in Kalamata, Greece, September 2021
Medical University of Vienna, Austria as presented at the Fifth Advances in Circulating Tumour Cells (ACTC) Meeting in Kalamata, Greece, September 2021
Detection of p53 aggregates in circulating tumour cells of patients with small cell lung cancer
Medical University of Vienna, Austria as presented at the Fifth Advances in Circulating Tumour Cells (ACTC) Meeting in Kalamata, Greece, September 2021
Mesenchymal markers: the new avenue for circulating tumor cells detection
ANGLE plc as presented at AACR 2021 Virtual Meeting, April / May 2021
ANGLE plc as presented at AACR 2021 Virtual Meeting, April / May 2021
University of Athens, Greece as presented at AACR 2019 in Atlanta, United States, March / April 2019
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Italy as presented at AACR 2019 in Atlanta, United States, March / April 2019
Northwestern University, Chicago, United States as presented at AACR 2019 in Atlanta, United States, March / April 2019
University of Athens, Greece as presented at AACR 2019 in Atlanta, United States, March / April 2019
Parsortix® system: Analytic performance evaluation using ovarian cancer cell lines
ANGLE plc as presented at AACR 2019 in Atlanta, United States, March / April 2019
Multiplex gene expression using the HyCEAD assay in CTCs isolated with the Parsortix® system
ANGLE plc as presented at AACR 2019 in Atlanta, United States, March / April 2019
ANGLE plc as presented at the 6th Annual Advances in Prenatal Molecular Diagnostics conference in Cambridge, MA, October 2018
ANGLE plc and QIAGEN GmbH as presented at the 11th International Symposium on Minimal Residual Cancer in Montpellier, France, May 2018 (ISMRC 2018)
Robert H Lurie Comprehensive Cancer Center and the Feinberg School of Medicine, Northwestern University, Chicago as presented at AACR 2018 in Chicago, April 2018
Bayer AG, Pharmaceutical Division as presented at AACR 2018 in Chicago, April 2018
University of Southern California Norris Comprehensive Cancer Center as presented at the San Antonio Breast Cancer Symposium in Texas, December 2017
ANGLE plc as presented at the AACC Emerging Clinical & Laboratory Diagnostics in the Healthcare Ecosystem (ECLD) conference in San Diego, November 2017
Universityclinic Tuebingen, Germany as presented at the Third International Advances in Circulating Tumour Cells (ACTC) Symposium in Rhodes, October 2017
Heinrich-Heine University Duesseldorf, Germany as presented at the Third International Advances in Circulating Tumour Cells (ACTC) Symposium in Rhodes, October 2017
Barts Cancer Institute, Queen Mary University of London as presented at the Third International Advances in Circulating Tumour Cells (ACTC) Symposium in Rhodes, October 2017
Single CTC isolation for genetic analysis using Parsortix® and VyCAP
VyCAP B.V. as presented at the Third International Advances in Circulating Tumour Cells (ACTC) Symposium in Rhodes, October 2017
MD Anderson as presented at the 68th AACC Annual Scientific Meeting & Clinical Lab Expo in Philadelphia, August 2016 (AACC 2016)
Fraunhofer ITEM as presented at the 24th Biennial Congress of the European Association for Cancer Research, July 2016 (EACR 2016)
A highly sensitive method for circulating tumor cell antigen quantification in liquid biopsy
ANGLE Research & Development Laboratory as presented at the 24th Biennial Congress of the European Association for Cancer Research, July 2016 (EACR 2016)
Cancer Research UK Manchester Institute as presented at the American Association for Cancer Research Annual Meeting 2016, April 2016
Heinrich-Heine University, Düsseldorf, Germany as presented at the 10th ISMRC International Symposium on Minimal Residual Cancer: Liquid Biopsy in Cancer Diagnostics and Treatment, March 2016
Cancer Research UK Manchester Institute, as presented at the 10th ISMRC International Symposium on Minimal Residual
Integration of RNA and DNA blood-borne cancer biomarkers
Cancer Research UK Manchester Institute, as presented at the 10th ISMRC International Symposium on Minimal Residual
Circulating rare cells enable highly efficient cancer detection
Medical University of Vienna, as presented at 18th ECCO – 40th ESMO European Cancer Congress September 2015
Intra-tumor heterogeneity in prostate cancer and the implication in CTC analysis
Barts Cancer Institute, as presented at a symposium hosted by the British Association for Cancer Research and Cancer Research UK on 11 June 2015
Circulating rare cells enable highly efficient cancer detection
Medical University of Vienna, as presented at the AACR conference April 2015
Enrichment and isolation of uncontaminated breast cancer cells from human blood samples
Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, as presented at the AACR conference April 2015
CRUK – Manchester, as presented at NCRI conference November 2014
Technical validation of a novel label-independent device to capture CTCs
The University Medical Center Hamburg-Eppendorf (UKE), as presented at ACTC Conference, October 2014
Articles
ANGLE achieves world first with FDA clearance for its Parsortix PC1 clinical system
Published by SHARES spotlight August 2022
ANGLE plc -Transforming cancer care with a liquid biopsy from a simple blood test
Published by SHARES spotlight May 2021
The impact of COVID-19 on cancer diagnosis and care
Andrew Newland, CEO ANGLE plc, published by European Biopharmaceutical Review, January 2021
Whitepapers
For Research Use Only. Not for use in diagnostic procedures.
Parsortix® Small Volume Capabilities
Parsortix® Cell Separation System Small Volume Capabilities
Presentations
Development of standardized epithelial and mesenchymal CTC + PD-L1 assay for Parsortix® system
Presentation to the American Association for Cancer Research conference September 7 – October 21, 2021
Presentation to the Sixth International Molecular Diagnostics Europe conference on 24 May 2018