Product solutions

Advancing CTC utilisation in research and clinical laboratories

ANGLE’s product solutions enable specialised circulating tumour cell (CTC) enrichment and downstream analysis within your laboratory

We offer user-friendly systems, leveraging our patented Parsortix® technology for efficient harvesting of CTCs and CTC clusters, as well as immunofluorescence kits for easy, reliable downstream analysis

Systems

ANGLE’s Parsortix technology is a unique CTC harvesting method using patented microfluidics in the form of a single use cassette, housed within an automated system.

 Blood processing in a lab

Parsortix PC1 system

CE marked and FDA cleared

The first FDA cleared medical device for the capture and harvest of intact CTCs from metastatic breast cancer patient blood for subsequent user-validated analysis.

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 A graphic representation of CTC harvesting in action

Parsortix PR1 system

For Research Use Only. Not For Use in Diagnostic Procedures.

Gives translational researchers the power to capture and harvest circulating tumor and other cells of interest from 100 μL to 40 mL blood samples, providing greater flexibility in downstream analysis.

Discover more
 Blood processing in a lab

Parsortix PC1 system

CE marked and FDA cleared

The first FDA cleared medical device for the capture and harvest of intact CTCs from metastatic breast cancer patient blood for subsequent user-validated analysis.

Discover more
 A graphic representation of CTC harvesting in action

Parsortix PR1 system

For Research Use Only. Not For Use in Diagnostic Procedures.

Gives translational researchers the power to capture and harvest circulating tumor and other cells of interest from 100 μL to 40 mL blood samples, providing greater flexibility in downstream analysis.

Discover more

Downstream analysis

ANGLE’s CTC test kits provide advanced immunofluorescent staining of CTCs enriched from blood by Parsortix technology.

 Portrait+ CTC Staining Kit by ANGLE PLC

Portrait® + CTC Staining kit

For Research Use Only. Not For Use in Diagnostic Procedures.

Enables the identification and enumeration of epithelial and mesenchymal cells including those undergoing epithelial-to-mesenchymal transition (EMT).

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 Portrait+ CTC Staining Kit by ANGLE PLC

Portrait® + CTC Staining kit

For Research Use Only. Not For Use in Diagnostic Procedures.

Enables the identification and enumeration of epithelial and mesenchymal cells including those undergoing epithelial-to-mesenchymal transition (EMT).

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An extension to your team

We will work with you to provide the best solution for your project including optimised and standardised workflows to ensure an efficient process and reproducible results.

 Lynsey has blonde hair, and is wearing a white blouse and dark blazer

Lynsey Zeolla

Head of Product Sales

Lynsey Zeolla is Head of Product Sales at ANGLE and is responsible for managing the team of Sales managers. Lynsey manages business relationships with Clinicians, Laboratory customers in research and clinical markets plus globally positioned Distributors.

Lynsey has 26 years of experience in customer focused scientific industries ranging from Molecular Diagnostics, Biotech and Forensic Science. She started her career as a forensic reporting scientist which led to the establishment and management of a high-throughput UKAS accredited forensic Serious Crime DNA Laboratory.

Since then, her career has been focused on commercial roles. Using knowledge gained in the Laboratory has allowed a strong appreciation of customer requirements which has strengthened relationships and contributed to her successes.

Lynsey has global Commercial sales experience and is an experienced manager with positions held at companies such as Abbott (formerly Alere Toxicology), LGC, Yourgene Health and Natera.

As an experienced manager Lynsey contributes to the strategic direction of ANGLE.

Connect with Lynsey
 A man wearing a white shirt, and dark blazer

Neil Darroch

Senior Sales Manager

Science has always been my passion

From my early years in school to my degree in Immunology from Glasgow University, learning about the latest advancements and breakthroughs in medical science has always made me optimistic for the future

Knowing that I was not cut out for lab work then I have made it the focus of my career to find other ways to support scientific and medical advancement

From Customer Service roles to Technical Support roles, from Key Account Management to Sales Management and Business Development, supporting the scientific and medical community has always been my focus

In the almost two decades since graduating from University I have worked for both large multinational research companies and small, start-up, medical diagnostic companies

It is the revolutionary potential of Liquid Biopsy to bring dramatic improvements to multiple stages of a cancer patients journey that attracted me to joining ANGLE

The wealth of information circulating tumour cells contain make them an ideal tool for understanding the metastatic process and translating these findings to actionable clinical tests. 

Connect with Neil
 Rob is wearing glasses, and a green and white checked shirt.

Rob Hollifield

Sales Manager

I have been involved with clinical science for over 30 years in Immunology, Molecular Diagnostics, Transplantation and Oncology.

I have worked in many laboratories and became HCPC- registered as a Clinical Scientist whilst working at NHS Blood and Transplant and moved into cancer diagnostics at the Royal Marsden Hospital, Sutton. Recently, I worked as a Clinical Scientist examining the clinical utility of Circulating Tumour Cells as a biomarker in liquid biopsies. 

In addition to my scientific background, I have over 6 years commercial experience as an UK Account Manager responsible for all Transplantation laboratories in the UK and Ireland.  

Connect with Rob
 Debora is wearing black glasses and a cream jumper

Debora Marchese

International Sales Manager

After my studies in both science and in international business, I started my career in Taiwan where I worked in a company called RBC Bioscience, manufacturer of instruments and kits for molecular diagnostics and research.

Working at RBC, I had the opportunity to introduce the MagCore system, for mag bead-based DNA/RNA extraction, all over the world, through a thick network of distributors in every continent, and through direct sales in Taiwan and China. During my years at the company, I have also had the pleasure to be involved in the launch of a new all-in-one instrument for NA extraction and qPCR detection. 

In 2020 I moved to the UK, where I helped RBC establish their first office overseas. Afterwards, I joined for the first time a Dutch distributor company called GC biotech., where I run the start-up branch in the UK, representing brands like S2 Genomics for single-cell harvest from solid tissue, and capital equipment in lab automation such as BioNex, Dynamic Devices, Genie and Grenova, and working with a plethora of clients, from pharma to university research institutes. 

In the past couple of years I have also sat at the Board of Directors of GAMBICA, the British association of laboratory technology companies, and of Gene Biotech, a Canadian company manufacturing COVID antibody tests. 

I joined ANGLE in 2024 where I have been working again in the area I am most passionate about: research and clinical international sales. 

Connect with Debora
 Lynsey has blonde hair, and is wearing a white blouse and dark blazer

Lynsey Zeolla

Head of Product Sales

Lynsey Zeolla is Head of Product Sales at ANGLE and is responsible for managing the team of Sales managers. Lynsey manages business relationships with Clinicians, Laboratory customers in research and clinical markets plus globally positioned Distributors.

Lynsey has 26 years of experience in customer focused scientific industries ranging from Molecular Diagnostics, Biotech and Forensic Science. She started her career as a forensic reporting scientist which led to the establishment and management of a high-throughput UKAS accredited forensic Serious Crime DNA Laboratory.

Since then, her career has been focused on commercial roles. Using knowledge gained in the Laboratory has allowed a strong appreciation of customer requirements which has strengthened relationships and contributed to her successes.

Lynsey has global Commercial sales experience and is an experienced manager with positions held at companies such as Abbott (formerly Alere Toxicology), LGC, Yourgene Health and Natera.

As an experienced manager Lynsey contributes to the strategic direction of ANGLE.

Connect with Lynsey
 A man wearing a white shirt, and dark blazer

Neil Darroch

Senior Sales Manager

Science has always been my passion

From my early years in school to my degree in Immunology from Glasgow University, learning about the latest advancements and breakthroughs in medical science has always made me optimistic for the future

Knowing that I was not cut out for lab work then I have made it the focus of my career to find other ways to support scientific and medical advancement

From Customer Service roles to Technical Support roles, from Key Account Management to Sales Management and Business Development, supporting the scientific and medical community has always been my focus

In the almost two decades since graduating from University I have worked for both large multinational research companies and small, start-up, medical diagnostic companies

It is the revolutionary potential of Liquid Biopsy to bring dramatic improvements to multiple stages of a cancer patients journey that attracted me to joining ANGLE

The wealth of information circulating tumour cells contain make them an ideal tool for understanding the metastatic process and translating these findings to actionable clinical tests. 

Connect with Neil
 Rob is wearing glasses, and a green and white checked shirt.

Rob Hollifield

Sales Manager

I have been involved with clinical science for over 30 years in Immunology, Molecular Diagnostics, Transplantation and Oncology.

I have worked in many laboratories and became HCPC- registered as a Clinical Scientist whilst working at NHS Blood and Transplant and moved into cancer diagnostics at the Royal Marsden Hospital, Sutton. Recently, I worked as a Clinical Scientist examining the clinical utility of Circulating Tumour Cells as a biomarker in liquid biopsies. 

In addition to my scientific background, I have over 6 years commercial experience as an UK Account Manager responsible for all Transplantation laboratories in the UK and Ireland.  

Connect with Rob
 Debora is wearing black glasses and a cream jumper

Debora Marchese

International Sales Manager

After my studies in both science and in international business, I started my career in Taiwan where I worked in a company called RBC Bioscience, manufacturer of instruments and kits for molecular diagnostics and research.

Working at RBC, I had the opportunity to introduce the MagCore system, for mag bead-based DNA/RNA extraction, all over the world, through a thick network of distributors in every continent, and through direct sales in Taiwan and China. During my years at the company, I have also had the pleasure to be involved in the launch of a new all-in-one instrument for NA extraction and qPCR detection. 

In 2020 I moved to the UK, where I helped RBC establish their first office overseas. Afterwards, I joined for the first time a Dutch distributor company called GC biotech., where I run the start-up branch in the UK, representing brands like S2 Genomics for single-cell harvest from solid tissue, and capital equipment in lab automation such as BioNex, Dynamic Devices, Genie and Grenova, and working with a plethora of clients, from pharma to university research institutes. 

In the past couple of years I have also sat at the Board of Directors of GAMBICA, the British association of laboratory technology companies, and of Gene Biotech, a Canadian company manufacturing COVID antibody tests. 

I joined ANGLE in 2024 where I have been working again in the area I am most passionate about: research and clinical international sales. 

Connect with Debora

Discover how ANGLE can help with your liquid biopsy needs

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