Lab Tech Molecular

ANGLE is a world-leading liquid biopsy company commercialising a patent protected platform technology that can capture rare circulating tumour cells (CTCs) from blood, in a minimally invasive way, for downstream analysis.

ANGLE’s Parsortix® system is FDA cleared for its intended use in metastatic breast cancer and is currently the first and only FDA cleared medical device to harvest intact circulating cancer cells from blood. Parsortix technology comprises a microfluidic device that captures CTCs from blood based on their size and compressibility. CTCs are cancer cells that have detached from the primary tumour and entered the blood circulation, and they play a critical role in initiating metastasis. Once harvested, the CTCs can be comprehensively analysed to provide a wealth of information about the patient’s tumour, advancing cancer research and potentially personalized medicine. This technology has the potential to deliver profound improvements in clinical and health economic outcomes.

ANGLE has established a CTC harvest and analysis service from our UK-based Clinical Laboratory based in Guildford for customers worldwide. In alignment with company priorities, we plan to rapidly expand our services to include molecular profiling of CTCs and ctDNA using digital PCR and NGS to add to our image-based assays.

This is an exciting time at ANGLE and our team in Guildford are looking for a Laboratory Technician (Molecular) to contribute to the smooth running of the laboratory and provide technical support to the scientific team. The job is laboratory-based working in a multi-disciplinary team. Goals and tasks are agreed weekly with supervisor.

The job holder will learn to follow standard operating procedures and handling instruments and reagents commonly used in biological labs. Moreover, the job holder will be able to understand the effects of their technical work supporting the team on weekly group updates.

This position provides invaluable lab experience and teamwork skills, and the opportunity to learn about and contribute to product development in an industry environment. This is a scientific support role and will involve repetitive tasks.

At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading-edge translational research into clinical diagnostics. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas.

We are always in search of potential employees who share our vision and want to make a difference today. In your submission, please describe your background and what you can bring to our team along with attaching your resume.

• Hands-on laboratory work, performing routine instrument maintenance and regular lab techniques: preparing and processing blood samples using the Parsortix instrument, DNA/RNA extraction, digital PCR, library preparation for NGS
• Contribute to data collection and recording according to ANGLE quality regulations
• With supervision and support, involved in data processing, analysis and reporting
• Provide technical support to other members of the team in various programs and projects in the area of Molecular
• Responsible for quality and regulatory compliance of work undertaken
• Contribute to running laboratory facilities, including receiving and unpacking deliveries, and adequate storing of them, formulating buffers and maintaining laboratory consumables as required
• Support all aspects of Laboratory Management in a variety of tasks both in and out of the lab as and when required by line manager
• Undertake additional ad-hoc tasks as required.​

• B.Sc. or equivalent in Life Sciences gained on a course that includes practical laboratory work, or equivalent combination of education and experience (e.g. ‘A’ Levels and demonstrable relevant laboratory experience).
• Experience of working to strict quality standards such as ISO9001 or preferably ISO3485 would be an advantage.
• Previous hands-on experience with at least one of the following techniques: qPCR, dPCR, or NGS (minimum 1 year).

Due to the nature of the role, our requirement is for this position to be Guildford-based, office hours, five days per week.

As a member of our highly skilled team you will receive opportunities for training and development and a competitive benefits package.

Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs.

Furthermore, please be advised that if you submit an application to us for this position, your application and personal details will be processed in accordance with our Data Privacy Notice for Job Candidates.