Laboratory Technician (Molecular Biology)

ANGLE is a world-leading liquid biopsy company commercialising a patent protected platform technology that can capture rare circulating tumour cells (CTCs) from blood, in a minimally invasive way, for downstream analysis.

ANGLE’s Parsortix® system is FDA cleared for its intended use in metastatic breast cancer and is currently the first and only FDA cleared medical device to harvest intact circulating cancer cells from blood. Parsortix technology comprises a microfluidic device that captures CTCs from blood based on their size and compressibility. CTCs are cancer cells that have detached from the primary tumour and entered the blood circulation, and they play a critical role in initiating metastasis. Once harvested, the CTCs can be comprehensively analysed to provide a wealth of information about the patient’s tumour, advancing cancer research and potentially personalized medicine. This technology has the potential to deliver profound improvements in clinical and health economic outcomes.

ANGLE has established a CTC harvest and analysis service from our UK-based Clinical Laboratory based in Guildford for customers worldwide. In alignment with company priorities, we plan to rapidly expand our services to include molecular profiling of CTCs and ctDNA using digital PCR and NGS to add to our image-based assays.​

This is an exciting time at ANGLE and our team in Guildford are looking for a Laboratory Technician (Molecular Biology) to contribute to the smooth running of the laboratory and provide technical support to the scientific team. This job is laboratory-based working in a multi-disciplinary team. Goals and tasks are agreed weekly with your supervisor.​

You will learn to follow standard operating procedures and handle instruments and reagents commonly used in biological labs. You will also be expected to understand the effects of your technical work and supporting the team with weekly group updates.​

This position provides invaluable lab experience and teamwork skills, and the opportunity to learn about and contribute to product development in an industry environment. This is a scientific support role and will involve repetitive tasks.

At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading edge translational research into clinical diagnostics. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas.

We are always in search of potential employees who share our vision and want to make a difference today. In your submission, please describe your background and what you can bring to our team along with attaching your resume.​

• Hands-on laboratory work, performing routine instrument maintenance and regular lab techniques: cataloguing and processing blood samples using the Parsortix instrument, nucleic acid extraction and downstream molecular techniques.
• Follow Standard Operating Procedures and Work Instructions following Good Laboratory Practises and in accordance to ANGLE Quality Management System (QMS).
• Contribute to data collection and recording following Good Documentation Practises and in accordance to ANGLE QMS.
• With supervision and support, be involved in data processing, analysis and reporting.
• Provide technical support to other members of the team in various programs and projects in the area of Molecular Biology
• Responsible for quality and regulatory compliance of work undertaken
• Contribute to running laboratory facilities, including receiving and unpacking deliveries, and adequate storing of them, formulating buffers and maintaining laboratory consumables as required.
• Support all aspects of Laboratory Management in a variety of tasks both in and out of the lab as and when required by line manager.
• Undertake additional ad-hoc tasks as required.​

• B.Sc. or equivalent in Life Sciences gained on a course that includes practical laboratory work, or equivalent combination of education and experience (e.g. ‘A’ Levels and demonstrable relevant laboratory experience).
• Experience of working to strict quality standards such as ISO9001 or preferably ISO13485 would be an advantage
• Experience with molecular techniques such as PCR, dPCR and Next Gen Sequencing would be highly advantageous.
• Strong team player
• Strong verbal and written communication skills
• Ability to multitask and prioritise to meet deadlines
• Ability to work both independently with minimal supervision as well as in a team environment
• Continuous learner with a keen appetite for cross-disciplinary work
• Entrepreneurial thinking and work ethic
• An eye for detail and commitment to high quality data
• A flexible, can-do approach to the requirements of the job​

Due to the nature of the role, our requirement is for this position to be Guildford based, office hours, five days per week.

Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs.

As a member of our highly skilled team you will receive opportunities for training and development and a competitive benefits package.

Furthermore, please be advised that if you submit an application to us for this position, your application and personal details will be processed in accordance with our Data Privacy Notice for Job Candidates.