Technical Support Scientist

ANGLE is a world-leading liquid biopsy company commercialising a patent protected platform technology that can capture rare circulating tumour cells (CTCs) from blood, in a minimally invasive way, for downstream analysis.

ANGLE’s Parsortix® system is FDA cleared for its intended use in metastatic breast cancer and is currently the first and only FDA cleared medical device to harvest intact circulating cancer cells from blood. Parsortix technology comprises a microfluidic device that captures CTCs from blood based on their size and compressibility. CTCs are cancer cells that have detached from the primary tumour and entered the blood circulation, and they play a critical role in initiating metastasis. Once harvested, the CTCs can be comprehensively analysed to provide a wealth of information about the patient’s tumour, advancing cancer research and potentially personalized medicine. This technology has the potential to deliver profound improvements in clinical and health economic outcomes.

ANGLE has established a CTC harvest and analysis service from our UK-based Clinical Laboratory based in Guildford for customers worldwide. In alignment with company priorities, we plan to rapidly expand our services to include molecular profiling of CTCs and ctDNA using digital PCR and NGS to add to our image-based assays.

This is an exciting time at ANGLE and our team in Guildford are looking for a Technical Support Scientist.

At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading-edge translational research into clinical diagnostics. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas.

We are always in search of potential employees who share our vision and want to make a difference today. In your submission, please describe your background and what you can bring to our team along with attaching your resume.

• Conduct qualification, calibration, and performance verification of all Parsortix instruments following repair or maintenance to ensure optimal functionality and compliance with specifications
• Document and maintain accurate records of calibration, qualification procedures, and results
• Work with the Application Specialist to provide technical support to customers, resolving product related inquiries and troubleshooting issues related to equipment performance, applications, and software integration
• Work closely with service engineers to identify and resolve biomechanical issues, contributing to root cause analysis and corrective actions.
• Assist in product improvements by providing feedback based on customer experiences and field observations
• Conduct FMEA to identify potential failure modes, assess their impact, and determine necessary actions to mitigate risks and enhance product reliability
• Collaborate with cross-functional teams to implement corrective and preventive actions based on FMEA findings
• Investigate all quality-related issues with Parsortix instruments, cassettes and CellKeep slides and carry out cassettes and CellKeep slides validation
• When required and in collaboration with the application specialist, train customers on proper use, maintenance, and troubleshooting of instruments to maximize uptime and performance
• Develop and update technical support documentation, FAQs, and training materials for both internal and external stakeholders.
• Identify recurring technical issues and collaborate with the R&D and engineering teams to implement preventive measures and product enhancements
• Participate in cross-functional projects to support new product development and testing
• Undertake additional ad-hoc tasks as required

• Bachelor’s degree in Cell Biology, Molecular Biology, Biomedical Engineering, or a related field
• Hands-on experience in a technical support, scientific, or engineering role, preferably within the biotech or life sciences industry
• Strong understanding of cell biology principles and laboratory techniques
• Proven experience in troubleshooting complex technical and biomechanical issues
• Familiarity with qualification and calibration processes for scientific instruments
• Experience in conducting and applying FMEA in a technical or engineering context
• Excellent problem-solving skills with a methodical approach to technical challenges
• Ability to work independently and collaboratively within a team environment
• Detail-oriented with a commitment to quality and continuous improvement
• Knowledge of Good Laboratory Practices (GLP) and regulatory and quality compliance standards
• Proficiency in technical documentation and report writing
• An eye for detail and commitment to high-quality data
• A flexible, can-do approach to the requirements of the job
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Due to the nature of the role, our requirement is for this position

to be Guildford-based, office hours, five days per week. As a member of our highly skilled team you will receive opportunities for training and development and a competitive benefits package.

Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs.

Furthermore, please be advised that if you submit an application to us for this position, your application and personal details will be processed in accordance with our Data Privacy Notice for Job Candidates.